According to a new study, the researchers working with mice report they have gained insight into why lung cancer rates are going up in women, including those who don’t smoke. Margie Clapper, co leader of the Cancer Prevention and Control Program at Fox Chase Center in Philadelphia, in a statement, “Previous work has suggested that estrogen may play a role in lung cancer, but no one has shown that smoke can actually accelerate the metabolism of estrogen within the lungs”.
The study involved 255 patients with advanced lung cancer. Researchers believe that the study sets a path for bringing personalized medicine into the care of the lung cancer patients. Researchers at the University of Texas M. D Anderson Cancer Center, said that Lung Cancer is the leading cancer killer, accounting for 28 percent of all the cancer deaths in the U. S Edward S. Kim , a cancer researcher at M. D Anderson said, “

“This is a first step to find biomarkers that may help supplant existing toxic therapies and to find the right population for a particular drug”. In a strategy called adaptive trial design, the randomization of the remaining patients was weighted to steer patients toward therapies they were likely to benefit from based on their biomarkers. Tyler Jacks, a cancer researcher at Massachusetts Institute of Technology and President of the AACR, said of the Battle trail, “This is the future. This is how drugs will be developed and clinical trials organized.” .